dc.contributor	Pelcl Martin, Ing. : 65541
dc.contributor.advisor	Chvojka Jiří, Ing. Ph.D. : 58591
dc.contributor.author	Horník, Kryštof
dc.date.accessioned	2019-11-11T17:54:29Z
dc.date.available	2019-11-11T17:54:29Z
dc.date.committed	2019-4-18
dc.date.defense	2019-05-20
dc.date.issued	2019-05-20
dc.date.submitted	2018-2-20
dc.date.updated	2019-5-20
dc.degree.level	Bc.
dc.description.abstract	Bakalarska prace se zabyva vyvojem unikatni struktury bunecneho nosice pomoci technologie FDM/FFM 3D tisku a naslednym biologickym testovanim s lidskymi bunkami v podobe in vitro testu. Cilem prace je vytvoreni takove struktury a jejiho fyzickeho modelu, ktery se v ramci tkanoveho inzenyrstvi s umyslem nahrady nefunkcni kostni, svalove ci chrupavcite tkane bude dal vyvijet az do stavu, kdy bude moznost takovyto scaffold otestovat in vivo metodami. Testovanymi materialy byly poly(- kaprolakton) a kyselina polymlecna. Oba materialy jsou v oboru tkanoveho inzenyrstvi siroce vyuzivany. Vysledkem prace bylo zjisteni, ze z kyseliny polymlecne se jednoznacne lepe tisklo a vysledne nosice byly jednotnejsi. Za nastavenych podminek biologickeho testovani vykazovala kyselina polymlecna taktez vyssi miru poctu a proliferace bunek MG-63, coz bylo dokazano MTT testem.	cs
dc.description.abstract	Bachelor thesis deals with development of a scaffold's unique structure using the FDM/FFM 3D printing as one of the methods of Rapid Prototyping and biological testing afterwards using the in vitro lab methods. The aim of this pursue is to develop such a structure and its physical model which is intended to replace dysfunctional bone, muscular or cartilage structures, that has certain properties and hence is suitable foradvanced in vivo testing. Materials used within this experiment were poly(- caprolactone) and polylactid acid. Bothmaterials are respected and widely used in the field of tissue engineering. The results of this work bring to the attention that printing the scaffolds using the polylactid acid was much easier and that such printed scaffolds manifested more of an equal physical appearance. The conditions set for biological testing also suited the polylactid acid better as these scaffolds showed higher rate of thriving MG-63 cells during the MTT testing.	en
dc.description.mark
dc.format	63 s. (73 703 znaků)
dc.format.extent	Ilustrace 2 .stl soubory
dc.identifier.signature	V 201901483
dc.identifier.uri	https://dspace.tul.cz/handle/15240/154099
dc.language.iso	cs
dc.relation.isbasedon	1. Wypych, G. Handbook of Polymers, 2011th ed.; ChemTec Publishing, 2011.
dc.relation.isbasedon
dc.relation.isbasedon	2. Arafat, M. T.; et al. Biomimetic composite coating on rapid prototyped scaffolds for bone tissue engineering. Acta Biomaterialia 2011, 7 (2), 809820.
dc.relation.isbasedon
dc.relation.isbasedon	3. Szojka, A.; et al. Biomimetic 3D printed scaffolds for meniscus tissue engineering. Bioprinting 2017, 8, 17.
dc.relation.isbasedon
dc.relation.isbasedon	4. Do, Anh-Vu et al. 3D Printing of Scaffolds for Tissue Regeneration Applications. Advanced healthcare materials 4.12 (2015): 17421762. PMC. Web. 25 Oct. 2017.
dc.rights	Vysokoškolská závěrečná práce je autorské dílo chráněné dle zákona č. 121/2000 Sb., autorský zákon, ve znění pozdějších předpisů. Je možné pořizovat z něj na své náklady a pro svoji osobní potřebu výpisy, opisy a rozmnoženiny. Jeho využití musí být v souladu s autorským zákonem https://www.mkcr.cz/assets/autorske-pravo/01-3982006.pdf a citační etikou https://knihovna.tul.cz/document/26	cs
dc.rights	A university thesis is a work protected by the Copyright Act. Extracts, copies and transcripts of the thesis are allowed for personal use only and at one?s own expense. The use of thesis should be in compliance with the Copyright Act. https://www.mkcr.cz/assets/autorske-pravo/01-3982006.pdf and the citation ethics https://knihovna.tul.cz/document/26	en
dc.rights.uri	https://knihovna.tul.cz/document/26
dc.rights.uri	https://www.mkcr.cz/assets/autorske-pravo/01-3982006.pdf
dc.subject	nanovlakna	cs
dc.subject	3D tisk	cs
dc.subject	tkanove inzenyrstvi	cs
dc.subject	bunecny nosic	cs
dc.subject	nanofibers	en
dc.subject	3D printing	en
dc.subject	tissue engineering	en
dc.subject	scaffolds	en
dc.title	Vývoj mikrovláknených buněčných nosičů pomocí metody Rapid Prototyping	cs
dc.title	Development of microfibrous cellular scaffolds using the methods of Rapid Prototyping	en
dc.type	bakalářská práce	cs
local.degree.abbreviation	Bakalářský
local.degree.discipline	TNT
local.degree.programme	Textil
local.degree.programmeabbreviation	B3107
local.department.abbreviation	KNT
local.faculty	Fakulta textilní	cs
local.faculty.abbreviation	FT
local.identifier.author	T15000246
local.identifier.stag	39643
local.identifier.verbis
local.identifier.verbis	kpw06585474
local.note.administrators	automat
local.poradovecislo	1483

Vývoj mikrovláknených buněčných nosičů pomocí metody Rapid Prototyping

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