SUTURE RETENTION STRENGTH OF BILAYER VASCULAR GRAFTS MADE OF PCL, PLA AND THEIR COPOLYMER

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dc.contributor.authorOzdemir, Suzan
dc.contributor.authorOztemur, Janset
dc.contributor.authorYolgosteren, Atif
dc.contributor.authorSezgin, Hande
dc.contributor.authorEnis, Ipek Yalcin
dc.contributor.organizationTechnická univerzita v Liberci
dc.date.accessioned2025-04-07T07:59:17Z
dc.date.available2025-04-07T07:59:17Z
dc.description.abstractThe mechanical characteristics of small-diameter vascular grafts, including factors like modulus, elasticity, compliance, burst strength, and suture retention strength, need to be in line with those of native blood vessels. Even a slight mismatch in mechanical properties between the graft and the native vessel can lead to graft failure. Suture retention strength, a critical mechanical aspect, represents the force needed to remove a stitch from the graft or cause the graft wall to rupture. This property is vital for preventing leaks, maintaining proper blood flow, aiding tissue healing, ensuring long-term durability, and reducing complications in vascular grafts. In this study, bilayered vascular grafts are fabricated by electrospinning using polycaprolactone (PCL), poly (lactic acid) (PLA), and poly(l-lactide-co-caprolactone) (PLCL) polymers. The actual suturing conditions of vascular scaffolds are simulated and how the choice of polymer for the inner layer affects suture retention strength is assessed. At the post-mechanical stage, the morphologies of the scaffolds are investigated to gain a clearer understanding of how the material reacts to applied forces. The findings reveal that all the fabricated bilayer vascular scaffolds exhibit excellent suture performance, with strength values exceeding 10 N, and that polymer selection for the inner layer for the grafts significantly influences the results. Blending PCL and PLA in the inner layer is found to reduce suture retention strength, while using neat polymers results in better retention strength. This experiment offers a more precise assessment of suture retention strength for bilayer vascular grafts, facilitating further optimization of tissueengineered grafts to meet specific mechanical requirements.cs
dc.formattext
dc.format.extent4 strany
dc.identifier.doi10.15240/tul/008/2025-1-015
dc.identifier.issn1335-0617
dc.identifier.urihttps://dspace.tul.cz/handle/15240/176808
dc.language.isocscs
dc.publisherTechnical University of Liberec
dc.publisher.abbreviationTUL
dc.relation.ispartofFibres and Textiles
dc.subjectSuture retention strengthcs
dc.subjectVascular graftscs
dc.subjectBlood vesselscs
dc.subjectTissue engineeringcs
dc.titleSUTURE RETENTION STRENGTH OF BILAYER VASCULAR GRAFTS MADE OF PCL, PLA AND THEIR COPOLYMERen
dc.typeArticleen
local.accessopen access
local.citation.epage79
local.citation.spage76
local.facultyFaculty of Textile Engineeringen
local.fulltextyesen
local.relation.issue1
local.relation.volume32
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