Cyclodextrin-Polypyrrole Coatings of Scaffolds for Tissue Engineering

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dc.contributor.authorLukášek, Jan
dc.contributor.authorHauzerová, Šárka
dc.contributor.authorHavlíčková, Kristýna
dc.contributor.authorStrnadová, Kateřina
dc.contributor.authorMašek, Karel
dc.contributor.authorStuchlík, Martin
dc.contributor.authorStibor, Ivan
dc.contributor.authorJenčová, Věra
dc.contributor.authorŘezanka, Michal
dc.date.accessioned2019-07-25T06:44:00Z
dc.date.available2019-07-25T06:44:00Z
dc.date.issued2019-03-11
dc.description.abstractPolypyrrole is one of the most investigated conductive polymers used for tissue engineering applications because of its advantageous properties and the ability to promote different cell types’ adhesion and proliferation. Together with β-cyclodextrin, which is capable of accommodating helpful biomolecules in its cavity, it would make a perfect couple for use as a scaffold for tissue engineering. Such scaffolds were prepared by the polymerisation of 6-(pyrrol-3-yl)hexanoic acid on polycaprolactone microfibres with subsequent attachment of β-cyclodextrin on the polypyrrole layer. The materials were deeply characterised by several physical and spectroscopic techniques. Testing of the cyclodextrin enriched composite scaffold revealed its better performance in in vitro experiments compared with pristine polycaprolactone or polypyrrole covered polycaprolactone scaffolds.cs
dc.format.extent11 strancs
dc.identifier.doi10.3390/polym11030459
dc.identifier.urihttps://dspace.tul.cz/handle/15240/152950
dc.identifier.urihttps://www.mdpi.com/2073-4360/11/3/459
dc.language.isocscs
dc.relation.ispartofPolymers
dc.subjectcyclodextrincs
dc.subjectpyrrolecs
dc.subjectpolypyrrolecs
dc.subjectpolycaprolactonecs
dc.subjectfunctionalisationcs
dc.subjectmicrofibrescs
dc.subjecttissue engineeringcs
dc.subjectscaffoldcs
dc.titleCyclodextrin-Polypyrrole Coatings of Scaffolds for Tissue Engineeringcs
local.relation.issue3
local.relation.volume11
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