Cytocompatibility of polyethylene grafted with triethylenetetramine functionalized carbon nanoparticles

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dc.contributor.authorŽáková Pavlínacs
dc.contributor.authorSlepičková Kasálková Nikolacs
dc.contributor.authorSlepička Petrcs
dc.contributor.authorKolská Zdeňkacs
dc.contributor.authorKarpíšková Janacs
dc.contributor.authorStibor Ivancs
dc.contributor.authorŠvorčík Václavcs
dc.date.accessioned2018-09-25T12:12:06Z
dc.date.available2018-09-25T12:12:06Z
dc.date.issued2017cs
dc.description.abstractVarious carbon nanostructures are widely researched as scaffolds for tissue engineering. We evaluated the surface properties and cell-substrate interactions of carbon nanoparticles functionalized with triethylenetetramine (CNPs) grafted polymer film. Two forms of polyethylene (HDPE, LDPE) were treated in an inert argon plasma discharge and, subsequently, grafted with CNPs. The surface properties were studied using multiple methods, including Raman spectroscopy, goniometry, atomic force microscopy, Xray photoelectron spectroscopy and electrokinetic analysis. Cell-substrate interactions were determined in vitro by studying adhesion, proliferation and viability of vascular smooth muscle cells (VSMCs) from the aorta of a rat. Cell-substrate interactions on pristine and modified substrates were compared to standard tissue culture polystyrene. Our results show that CNPs affect surface morphology and wettability and therefore adhesion, proliferation and viability of cultured muscle cells.en
dc.format.extent8cs
dc.identifier.doi10.1016/j.apsusc.2017.06.089
dc.identifier.issn0169-4332cs
dc.identifier.urihttps://dspace.tul.cz/handle/15240/30903
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0169433217317452
dc.language.isoengcs
dc.relation.ispartofseries0cs
dc.relation.urihttp://www.sciencedirect.com/science/article/pii/S0169433217317452cs
dc.subjectPolymer graftingcs
dc.subjectCarbon nanoparticlescs
dc.subjectCytocompatibilitycs
dc.subjectCell-substrate interactionscs
dc.subjectWettabilitycs
dc.titleCytocompatibility of polyethylene grafted with triethylenetetramine functionalized carbon nanoparticlescs
local.citation.epage809-816cs
local.citation.spage809-816cs
local.identifier.publikace4356
local.identifier.wok410606900095en
local.relation.issueNovembercs
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