Posouzení vlivu bypassu na charakter proudění karotidou metodami Global Imaging
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Hlavním cílem práce bylo vytvořit bypass při uzávěru tepny v povodí karotické bifurkace a posoudit jeho vliv na charakter proudění karotidou metodou Global Imaging. Byla provedena série měření pomocí měřící metody Particle Image Velocimetry. Experimentální měření jasně prokázalo, že tvar a úhel napojení bypassu, jsou rozhodujícími parametry. Tyto parametry ve výsledku ovlivní lokální hemodynamiku - změna charakteru proudící kapaliny, a především smykového napětí v blízkosti stěny cévy. Takto nově vzniklé hemodynamické děje hrají klíčovou roli ve vzniku, progresi a lokalizaci tromboembolismu, stenotických plátů, nebo uzavření bypassu.
The main goal of this work was to create a bypass at the closure of an artery in the basin of carotid bifurcation and to assess its effect on the nature of carotid flow using the Global Imaging method. A series of measurements was performed using the Particle Image Velocimetry measurement method. Experimental measurements have clearly shown that the shape and angle of the bypass connection are crucial parameters. As a result, these parameters affect local hemodynamics - a change in the character of the flowing fluid, and especially the shear stress near the vessel wall. Such newly formed hemodynamic events play a key role in the origin, progression and localization of thromboembolism, stenotic plaques, or bypass closure.
The main goal of this work was to create a bypass at the closure of an artery in the basin of carotid bifurcation and to assess its effect on the nature of carotid flow using the Global Imaging method. A series of measurements was performed using the Particle Image Velocimetry measurement method. Experimental measurements have clearly shown that the shape and angle of the bypass connection are crucial parameters. As a result, these parameters affect local hemodynamics - a change in the character of the flowing fluid, and especially the shear stress near the vessel wall. Such newly formed hemodynamic events play a key role in the origin, progression and localization of thromboembolism, stenotic plaques, or bypass closure.
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karotická bifurkace, karoticko-subklaviální bypass, fantom krve, smykové napětí, pulzatilní tok, hemodynamika, Global Imaging metoda, Particle Image Velocimetry, carotid bifurcation, carotid-subclavian bypass, phantom blood, shear stress, pulsatile flow, hemodynamics, Global Imaging method, Particle Image Velocimetry