Browsing by Author "Beltran-Mir, H."

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    Ag Nanoparticles/alpha-Ag2WO4 Composite Formed by Electron Beam and Femtosecond Irradiation as Potent Antifungal and Antitumor Agents
    (2019-07-23) Assisi, M.; Robeldo, T.; Foggi, C. C.; Kubo, A. M.; Minguez-Vega, G.; Condoncillo, E.; Beltran-Mir, H.; Torres-Mendieta, R.; Andres, J.; Oliva, M.; Vergani, C. E.; Barbugli, P. A.; Camargo, E. R.; Borra, R. C.; Longo, E.
    The ability to manipulate the structure and function of promising systems via external stimuli is emerging with the development of reconfgurable and programmable multifunctional materials. Increasing antifungal and antitumor activity requires novel, efective treatments to be diligently sought. In this work, the synthesis, characterization, and in vitro biological screening of pure α-Ag2WO4, irradiated with electrons and with non-focused and focused femtosecond laser beams are reported. We demonstrate, for the frst time, that Ag nanoparticles/α-Ag2WO4 composite displays potent antifungal and antitumor activity. This composite had an extreme low inhibition concentration against Candida albicans, cause the modulation of α-Ag2WO4 perform the fungicidal activity more efcient. For tumor activity, it was found that the composite showed a high selectivity against the cancer cells (MB49), thus depleting the populations of cancer cells by necrosis and apoptosis, without the healthy cells (BALB/3T3) being afected.
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    Laser and electron beam-induced formation of Ag/Cr structures on Ag2CrO4
    (ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND, 2019-03-21) Lemos, P. S.; Silva, G. S.; Roca, R. A.; Assis, M.; Torres-Mendieta, Rafael Omar; Beltran-Mir, H.; Minguez-Vega, G.; Cordoncillo, E.; Andres, J.; Longo, E.
    The interactions of silver chromate (Ag2CrO4) with a femtosecond (fs) laser and electron beam irradiations were investigated. For the first time, the growth and coalescence of metallic Ag nanoparticles (NPs) on an Ag2CrO4 surface via fs laser irradiation can be reported. Furthermore, electron beam irradiation causes a segregation process of Ag NPs in which Ag nanofilaments are obtained. The Ag2CrO4 particles were characterized using X-ray diffraction (XRD), micro-Raman spectroscopy (Raman), field-emission scanning electron microscopy (FE-SEM), high-resolution electron microscopy, and energy-dispersive X-ray spectroscopy (EDS). According to the results, the fs/electron beam irradiations of Ag2CrO4 are environmentally friendly, fast, and effective methods to produce metallic Ag NPs. Both strategies have enormous potential for the synthesis and morphological control of Ag NPs on templates or biotemplates, core-shells, decorations, and composites based on Ag2-xCrO4:Ag materials, which are difficult to synthesize using conventional chemical and physical methods.