Electron-Beam Irradiation of the PLLA/CMS/beta-TCP Composite Nanofibers Obtained by Electrospinning

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dc.contributor.authorYusof, Mohd Reusmaazran
dc.contributor.authorShamsudin, Roslinda
dc.contributor.authorZakaria, Sarani
dc.contributor.authorHamid, Muhammad Azmi Abdul
dc.contributor.authorYalcinkaya, Fatma
dc.contributor.authorAbdullah, Yusof
dc.contributor.authorYacob, Norzita
dc.date.accessioned2020-08-25T07:09:04Z
dc.date.available2020-08-25T07:09:04Z
dc.date.issued2020-07
dc.description.abstractNanofibrous materials produced by electrospinning processes have potential advantages in tissue engineering because of their biocompatibility, biodegradability, biomimetic architecture, and excellent mechanical properties. The aim of the current work is to study the influence of the electron beam on the poly L-lactide acid/ carboxy-methyl starch/beta-tricalcium phosphate (PLLA/CMS/beta-TCP) composite nanofibers for potential applications as bone-tissue scaffolds. The composite nanofibers were prepared by electrospinning in the combination of 5%v/vcarboxy-methyl starch (CMS) and 0.25 wt% of beta-TCP with the PLLA as a matrix component. The composites nanofibers were exposed under 5, 30, and 100 kGy of irradiation dose. The electron-beam irradiation showed no morphological damage to the fibers, and slight reduction in the water-contact angle and mechanical strength at the higher-irradiation doses. The chain scission was found to be a dominant effect; the higher doses of electron-beam irradiation thus increased the in vitro degradation rate of the composite nanofibers. The chemical interaction due to irradiation was indicated by the Fourier transform infrared (FTIR) spectrum and thermal behavior was investigated by a differential scanning calorimeter (DSC). The results showed that the electron-beam-induced poly L-lactide acid/carboxy-methyl starch/beta-tricalcium phosphate (PLLA/CMS/beta-TCP) composite nanofibers may have great potential for bone-tissue engineering.cs
dc.format.extent16 strancs
dc.identifier.WebofScienceResearcherIDA-2141-2014 Yalcinkaya, Fatma
dc.identifier.doi10.3390/polym12071593
dc.identifier.orcid0000-0002-5057-3718 Yalcinkaya, Fatma
dc.identifier.urihttps://dspace.tul.cz/handle/15240/157461
dc.identifier.urihttps://www.mdpi.com/2073-4360/12/7/1593
dc.language.isocscs
dc.publisherMDPI
dc.relation.ispartofPolymers 2020
dc.subjectPLLAcs
dc.subjectcarboxy-methyl starchcs
dc.subjectbeta-tricalcium phosphatecs
dc.subjectelectrospuncs
dc.subjectbiodegradationcs
dc.titleElectron-Beam Irradiation of the PLLA/CMS/beta-TCP Composite Nanofibers Obtained by Electrospinningcs
local.article.number1593
local.relation.issue7
local.relation.volume12
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