How does the surface treatment change the cytocompatibility of implants made by Selective Laser Melting?

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dc.contributor.authorAckermann Michalcs
dc.contributor.authorHoráková Janacs
dc.contributor.authorČapek Lukášcs
dc.contributor.authorHenyš Petrcs
dc.contributor.authorŠafka Jiřícs
dc.contributor.authorMatoušková Luciecs
dc.date.accessioned2018-09-25T11:51:31Z
dc.date.available2018-09-25T11:51:31Z
dc.date.issued2018cs
dc.description.abstractIntroduction: The study investigates the potential for producing medical components via Selective Laser Melting technology (SLM). The material tested consisted of the biocompatible titanium alloy Ti6Al4V. The research involved the testing of laboratory specimens produced using SLM technology both in vitro and for surface roughness. The aim of the research was to clarify whether SLM technology affects the cytocompatibility of implants and, thus, whether SLM implants provide suitable candidates for medical use following zero or minimum post-fabrication treatment. Areas covered: The specimens were tested with an osteoblast cell line and, subsequently, two post-treatment processes were compared: non-treated (as-fabricated) and glass-blasted. Interactions with MG-63 cells were evaluated by means of metabolic MTT assay and microscope techniques (scanning electron microscopy, fluorescence microscopy). Surface roughness was observed on both the non-treated and glass-blasted SLM specimens. Expert Commentary: The research concluded that the glass-blasting of SLM Ti6Al4V significantly reduces surface roughness. The arithmetic mean roughness Ra was calculated at 3.4 µm for the glass-blasted and 13.3 µm for the non-treated surfaces. However, the results of in vitro testing revealed that the non-treated surface was better suited to cell growth.en
dc.format.extent9cs
dc.identifier.doi10.1080/17434440.2018.1456335
dc.identifier.issn1743-4440cs
dc.identifier.urihttps://dspace.tul.cz/handle/15240/27790
dc.language.isoengcs
dc.publisherTaylor & Franciscs
dc.relation.ispartofseries0cs
dc.relation.urihttps://www.tandfonline.com/doi/abs/10.1080/17434440.2018.1456335?journalCode=ierd20cs
dc.subjectSelective laser meltingcs
dc.subjectTi6Al4Vcs
dc.subjectindividual medical implantscs
dc.subjectsurface roughnesscs
dc.subjectin vitro testingcs
dc.subjectselective laser meltingen
dc.subjectTi6Al4Ven
dc.subjectindividual medical implantsen
dc.subjectsurface roughnessen
dc.subjectin vitro testingen
dc.titleHow does the surface treatment change the cytocompatibility of implants made by Selective Laser Melting?en
dc.titleHow does the surface treatment change the cytocompatibility of implants made by Selective Laser Melting?cs
local.citation.epage313-321cs
local.citation.spage313-321cs
local.identifier.publikace1113
local.relation.issue4cs
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