The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters

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dc.contributor.authorHoráková Janacs
dc.contributor.authorMikeš Petrcs
dc.contributor.authorŠaman Alešcs
dc.contributor.authorJenčová Věracs
dc.contributor.authorKlápšťová Andreacs
dc.contributor.authorŠvarcová Terezacs
dc.contributor.authorAckermann Michalcs
dc.contributor.authorNovotný Vítcs
dc.contributor.authorSuchý Tomášcs
dc.contributor.authorLukáš Davidcs
dc.date.accessioned2018-09-25T12:19:45Z
dc.date.available2018-09-25T12:19:45Z
dc.date.issued2018cs
dc.description.abstractThe study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.en
dc.format.extent11cs
dc.identifier.doi10.1016/j.msec.2018.06.041
dc.identifier.issn0928-4931cs
dc.identifier.urihttps://dspace.tul.cz/handle/15240/32006
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0928493117338821
dc.language.isoengcs
dc.publisherELSEVIER SCIENCE BVcs
dc.publisher.cityNetherlandscs
dc.relation.ispartofseries0cs
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S0928493117338821cs
dc.rights.SHERPA/RoMEOMaterials Science and Engineering: C (ISSN: 0928-4931), author cannot archive publisher's version/PDF
dc.subjectEthylene oxide sterilizationcs
dc.subjectNanofiberscs
dc.subjectPolyesterscs
dc.subjectVascular graftscs
dc.titleThe effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyestersen
dc.titleThe effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesterscs
local.citation.epage132-142cs
local.citation.spage132-142cs
local.identifier.publikace5477
local.identifier.wok000414886400037en
local.relation.issueNOVcs
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