Incidence of takotsubo syndrome in patients with acute coronary syndrome: A single PCI center experience - A 7-years retrospective analysis

Title Alternative:Incidence Takotsubo syndromu u pacientu s akutním koronárním syndromem: retrospektivní 7letá analýza jednoho PCI centra
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dc.contributor.authorHolm, František
dc.contributor.authorVojáček, Jan
dc.contributor.authorErbrt, Miroslav
dc.contributor.authorHlaváček, Karel
dc.contributor.authorSurovčík, Roman
dc.contributor.authorFeuereisel, Rudolf
dc.date.accessioned2019-08-27T08:19:02Z
dc.date.available2019-08-27T08:19:02Z
dc.date.issued2019-01-01
dc.description.abstractTakotsubo syndrome is manifested with acute heart failure and resembles acute coronary syndrome, truly mimicking its clinical and ECG features. It is characterized by transient contractility disorder of predominantly the apical part of the left ventricle without any presence of occlusive coronary disease. It is found in 1-2% of patients admitted to hospital for acute coronary syndrome. The prognosis has so far been considered to be benign with complete recovery of the left ventricle within several weeks; however recent information from a large registry of this syndrome (InterTAK) has shown the short - and long-term prognosis to be the same as in patients suffering from acute coronary syndrome. The etiology is unknown and treatment is symptomatic only. Transient dynamic left ventricular outflow tract obstruction as well as hemodynamic instability and arrhythmias can sometimes be present. Aim of study: Retrospective analysis of the incidence and clinical course of takotsubo syndrome (TS) in patients with acute coronary syndrome (ACS) in a single PCI centre during an 84-month period. Results: A total of 2 298 urgent coronary angiography procedures were performed in patients presenting with ACS. The diagnosis of TS was established in 21 (0.9 %), with the majority of patients being female - 20 (95 %). The mean age was 63.7 ± 10.5 (49-84) years; ac- cording to ECG, there were 9 (43 %) STEMI and 12 (57 %) NSTEMI cases. The mean value of left ventricular ejection fraction (LVEF) was 47 ± 9.1 % (35-65 %). After one month, a complete restoration of LVEF was found in all patients undergoing follow-up (86 %) with a mean LVEF of 63.5 ± 8.9 % (50-80 %). None of the patients died within one month after the diagnosis of TS syndrome. Conclusion: Our experience confirms a low incidence of TS in patients with ACS. However, our study population is too small to obtain a valid conclusion on short-term prognosis.cs
dc.identifier.urihttps://dspace.tul.cz/handle/15240/153342
dc.identifier.urihttps://www.iakardiologie.cz/artkey/kar-201902-0003_incidence_takotsubo_syndromu_u_pacientu_s_akutnim_koronarnim_syndromem_retrospektivni_7leta_analyza_jednoho_pc.php
dc.language.isocscs
dc.relation.ispartofIntervencni a Akutni Kardiologie
dc.subjectAcute coronary syndromecs
dc.subjectComplicationcs
dc.subjectEtiologycs
dc.subjectIncidencecs
dc.subjectPrognosiscs
dc.subjectTakotsubo syndromecs
dc.subjectTreatmentcs
dc.titleIncidence of takotsubo syndrome in patients with acute coronary syndrome: A single PCI center experience - A 7-years retrospective analysiscs
dc.title.alternativeIncidence Takotsubo syndromu u pacientu s akutním koronárním syndromem: retrospektivní 7letá analýza jednoho PCI centra
local.citation.epage72
local.citation.spage68
local.relation.issue2
local.relation.volume18
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