The combination of meltblown technology and electrospinning - The influence of the ratio of micro and nanofibers on cell viability

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dc.contributor.authorErben, Jakub
dc.contributor.authorJenčová, Věra
dc.contributor.authorChvojka, Jiří
dc.contributor.authorBlažková, Lenka
dc.contributor.authorStrnadová, Kateřina
dc.contributor.authorModrak, Miroslav, Košťáková Kuželová Eva
dc.date.accessioned2016-06-30
dc.date.available2016-06-30
dc.date.issued2016
dc.description.abstractThis study describes the production, testing and characterization of biodegradable scaffolds for bone tissue, which consist of the exact ratio of meltblown microfibers and nanofibers produced through the electrostatic field. All fibrous materials were produced from polycaprolactone. Three kinds of materials were prepared in the experiment with the same area density and with different well-defined ratio of microfibers as a mechanical component and nanofibers as a cells adherent component. All prepared materials showed optimum porosity of the inner structure for cell proliferation and in comparison to the materials with nanofibers they had good mechanical properties. Important structural properties and homogenity of each material were observed by electron microscopy and analyzed by image analysis. The effect of various ratios of microfibers and nanofibers on adhesion and proliferation of osteoblasts in-vitro was characterized. © 2016 Elsevier B.V. All rights reserved.en
dc.identifier.doi10.1016/j.matlet.2016.02.147
dc.identifier.issn0167577X
dc.identifier.scopus2-s2.0-84961168428
dc.identifier.urihttps://dspace.tul.cz/handle/15240/16537
dc.language.isoen
dc.publisherElsevier
dc.publisherTechnical University of Liberec, Czech Republicen
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dc.relation.ispartofMaterials Letters
dc.relation.ispartofKatedra netkaných textilií a nanovlákenných materiálů
dc.sourceScopus
dc.subjectElectrospinningen
dc.subjectMeltblown technologyen
dc.subjectNanofibersen
dc.subjectPolycaprolactoneen
dc.subjectScaffolden
dc.subjectTissue engineeringen
dc.titleThe combination of meltblown technology and electrospinning - The influence of the ratio of micro and nanofibers on cell viabilityen
dc.typeArticle
local.citation.epage157
local.citation.spage153
local.fulltextnecs
local.fulltextyes
local.identifier.codenMLETD
local.relation.volume173
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