Carbon nanostructures grafted biopolymers for medical applications

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dc.contributor.authorSlepičková Kasálková, Nikola
dc.contributor.authorŽáková, Pavlína
dc.contributor.authorStibor, Ivan
dc.contributor.authorSlepička, Petr
dc.contributor.authorKolská, Zdeňka
dc.contributor.authorKarpíšková, Jana
dc.contributor.authorŠvorčík, Václav
dc.date.accessioned2019-08-01T06:20:30Z
dc.date.available2019-08-01T06:20:30Z
dc.date.issued2019-06-07
dc.description.abstractEnhancing biopolymers with carbon nanostructures leads to the creation of attractive materials suitable for diverse medical application. We studied surface properties and cytocompatibility of amine functionalised carbon nanoparticles (CNPs) grafted on biopolymer film. Poly-L-lactic acid and poly-3-hydroxybutyrate were treated in an inert argon plasma discharge and subsequently grafted with three types of amine-functionalised CNPs. The surface properties of (i) CNPs and (ii) grafted CNPs were studied using multiple methods. BET, electrokinetic and XPS analyses confirmed the successful grafting of amino-compounds on the surface and also into the pores of CNPs. Goniometry approved the binding of the modified CNPs on the polymer surface. From AFM is evident that both the biopolymers show completely changed surface morphology after grafting of CNPs. The cytocompatibility test with vascular smooth muscle cells showed that the presence of the modified CNPs on polymer substrates has a more positive effect on cytocompatibility of PLLA rather than PHB.cs
dc.format.extent11 strancs
dc.identifier.doi10.1080/10667857.2019.1573943
dc.identifier.urihttps://dspace.tul.cz/handle/15240/153024
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/10667857.2019.1573943
dc.language.isocscs
dc.relation.ispartofMATERIALS TECHNOLOGY
dc.subjectcytocompatibilitycs
dc.subjectsurface propertiescs
dc.subjectamine functionalisationcs
dc.subjectcarbon nanoparticlescs
dc.subjectgraftingcs
dc.subjectBiopolymerscs
dc.titleCarbon nanostructures grafted biopolymers for medical applicationscs
local.citation.epage385
local.citation.spage376
local.identifier.publikace6805
local.relation.issue7
local.relation.volume34
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