The Effect of Fatty Acids and BSA Purity on Synthesis and Properties of Fluorescent Gold Nanoclusters

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dc.contributor.authorAndrýsková, Pavlína
dc.contributor.authorMachalová Šišková, Karolína
dc.contributor.authorMichetschlägerová, Šárka
dc.contributor.authorJiráková, Klára
dc.contributor.authorKubala, Martin
dc.contributor.authorJirák, Daniel
dc.date.accessioned2020-03-03T08:16:42Z
dc.date.available2020-03-03T08:16:42Z
dc.date.issued2020-02
dc.description.abstractFluorescent gold nanoclusters (AuNCs) are envisaged as a novel type of fluorophores. This work reports on the first comparative study investigating the effect of presence/absence/abundance of fatty acids (namely palmitic acid, PA) or other substances (like glycoproteins and globulins) in the protein (bovine serum albumin, BSA) on synthesis and properties of the final AuNCs. The most popular template (BSA) and microwave (MW)-assisted synthesis of AuNCs have been intentionally chosen. Our results clearly demonstrate that the fluorescent characteristics (i.e., fluorescence lifetime and quantum yield) are affected by the fatty acids and/or other substances. Importantly, the as-prepared AuNCs are biocompatible, as determined by Alamar Blue assay performed on Hep G2 cell line.cs
dc.format.extent20 strancs
dc.identifier.doi10.3390/nano10020343
dc.identifier.urihttps://dspace.tul.cz/handle/15240/154601
dc.identifier.urihttps://www.mdpi.com/2079-4991/10/2/343
dc.language.isocscs
dc.publisherMDPI
dc.relation.ispartofNanomaterials
dc.subjectAu nanoclustercs
dc.subjectCell viabilitycs
dc.subjectFatty acidcs
dc.subjectPalmitic acidcs
dc.subjectSerum albumincs
dc.titleThe Effect of Fatty Acids and BSA Purity on Synthesis and Properties of Fluorescent Gold Nanoclusterscs
local.accessopen access
local.article.number343
local.identifier.publikace7235
local.relation.issue2
local.relation.volume10
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