Browsing by Author "Pavlíková Tereza"
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- ItemAnalysis of small diameter vascular grafts made from biodegradable polyesters(2015) Horáková Jana; Novák Patrik; Klápšťová Andrea; Pavlíková Tereza; Šaman Aleš; Ackermann Michal; Mikeš Petr
- ItemAssessment of cell adhesion on electrospun polycaprolactone scaffold sterilized by ethylene oxide(2017) Horáková Jana; Pavlíková Tereza; Šaman Aleš; Klápšťová Andrea; Mikeš Petr; Jenčová Věra
- ItemComprehensive assessment of electrospun scaffolds hemocompatibility(Elsevier BV, 2018) Horáková Jana; Mikeš Petr; Šaman Aleš; Pavlíková Tereza; Jenčová Věra; Suchý Tomáš; Heczková Bohdana; Jakůbková Šárka; Jiroušová Jaroslava; Procházková RenataBiodegradable polyesters, namely polycaprolactone (PCL) and copolymer of polylactide and polycaprolactone (PLCL) were electrospun into various fibrous structures and their hemocompatibility was evaluated in vitro. Firstly, hemolytic effect was evaluated upon incubation with diluted whole blood. The results showed that the degree of hemolysis depended on chemical composition and fibrous morphology. Electrospun polycaprolactone induced slight degree of hemolysis depending on its molecular weight and fibrous morphology; copolymer PLCL did not cause detectable hemolysis. The influence of coagulation pathways was examined by measurement of coagulation times. It was showed that intrinsic coagulation pathway assessed by activated partial thromboplastin time (APTT) was moderately accelerated after incubation with PCL and prolonged after incubation with copolymer PLCL. Extrinsic activation of coagulation tested by prothrombin time (PT) was slightly accelerated after incubation with all tested electrospun samples. Thrombogenicity assessment of fibrous samples revealed high thrombogenic properties of fibrous materials that was comparable to high degree of collagen thrombogenicity. The level of platelet activation was dependent on chemical composition and surface morphology of tested materials.
- ItemDegradation behavior of the polyester nanofibrous vascular grafts(2016) Jenčová Věra; Horáková Jana; Mikeš Petr; Strnadová Kateřina; Pavlíková Tereza; Vejsadová Lucie
- ItemHemocompatibility of nanofibrous materials(2016) Kaláb Martin; Jakůbková Šárka; Mikeš Petr; Heczková Bohdana; Horáková Jana; Suchý Tomáš; Procházková Renata; Lonský Vladimír; Jiroušová Jaroslava; Pavlíková Tereza
- ItemImpact of 3D scaffolds functionalized by platelete growth factors on the cell proliferation(2015) Jenčová Věra; Strnadová Kateřina; Horáková Jana; Pavlíková Tereza; Erben Jakub; Chvojka Jiří; Procházková Renata
- ItemPlatelet interaction with nano- and microfibrous materials for the tissue engineering(2016) Jenčová Věra; Procházková Renata; Horáková Jana; Strnadová Kateřina; Pavlíková Tereza
- ItemThe Combination of Three - Dimensional Biodegradable Fiber Scaffolds with Bioprinting(TANGER Ltd., 2016) Erben Jakub; Jirkovec Radek; Novák Patrik; Pelcl Martin; Pavlíková Tereza; Chvojka Jiří