Browsing by Author "Makvandi, Pooyan"
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- ItemAntimicrobial gum bio-based nanocomposites and their industrial and biomedical applications(ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND, 2019-01-01) Zare, Ehsan Nazarzadeh; Makvandi, Pooyan; Borzacchiello, Assunta; Tay, Franklin R.; Ashtari, Behnaz; Padil, Vinod V. T.Gum polysaccharides are derived from renewable sources. They are readily available, inexpensive, non-hazardous and eco-friendly. Depending upon the source, gums may be categorized as microbial gums, plant exudate gums or seed gums. Naturally occurring gum carbohydrates find multiple applications in the biomedical arena, compared with synthetic compounds, because of their unique structures and functionalities. Gums and their biocomposites are preferred for sustained drug delivery because they are safe and edible as well as more susceptible to biodegradation. The present review provides a state-of-the-art conspectus on the industrial and biomedical applications of antimicrobial gum-based biocomposites. Different kinds of gums polysaccharides will first be addressed based on their sources. Metal-, carbon- and organic-based nanostructures that are used in gum nanocomposites will then be reviewed with respect to their industrial and biomedical applications, to provide a backdrop for future research.
- ItemFunctionalization of Polymers and Nanomaterials for Biomedical Applications: Antimicrobial Platforms and Drug Carriers(MDPI, 2020-06-23) Delfi, Masoud; Ghomi, Matineh; Zarrabi, Ali; Mohammadinejad, Reza; Baghban, Taraghdari Zahra; Ashrafizadeh, Milad; Nazarzadeh Zare, Ehsan; Agarwal, Tarun; Padil, Vinod V. T.; Mokhtari, Babak; Rossi, Filippo; Perale, Giuseppe; Sillanpaa, Mika; Borzacchiello, Assunta; Maiti, Tapas Kumar; Makvandi, PooyanThe use of polymers and nanomaterials has vastly grown for industrial and biomedical sectors during last years. Before any designation or selection of polymers and their nanocomposites, it is vital to recognize the targeted applications which require these platforms to be modified. Surface functionalization to introduce the desired type and quantity of reactive functional groups to target a cell or tissue in human body is a pivotal approach to improve the physicochemical and biological properties of these materials. Herein, advances in the functionalized polymer and nanomaterials surfaces are highlighted along with their applications in biomedical fields, e.g., antimicrobial therapy and drug delivery.