Browsing by Author "Bartoš Martin"

Now showing 1 - 3 of 3
  • Item
    Electrospun vascular grafts fabricated from poly(L-lactide-co-epsilon-caprolactone) used as a bypass for the rabbit carotid artery
    (IOP Publishing, 2018-01-01) Horáková Jana; Mikeš Petr; Lukáš David; Šaman Aleš; Jenčová Věra; Klápšťová Andrea; Švarcová Tereza; Ackermann Michal; Novotný Vít; Kaláb Martin; Lonský Vladimír; Bartoš Martin; Rampichova Michala; Litvinec Andrej; Kubíková Tereza; Tomášek Petr; Tonar Zbyněk
    The study involved the electrospinning of the copolymer poly(L-lactide-co-ε-caprolactone) (PLCL) into tubular grafts. The subsequent material characterization, including micro-computed tomography analysis, revealed a level of porosity of around 70%, with pore sizes of 9.34 ± 0.19 μm and fiber diameters of 5.58 ± 0.10 μm. Unlike fibrous polycaprolactone, the electrospun PLCL copolymer promoted fibroblast and endothelial cell adhesion and proliferation in vitro. Moreover, the regeneration of the vessel wall was detected following implantation and, after six months, the endothelialization of the lumen and the infiltration of arranged smooth muscle cells producing collagen was observed. However, the degradation rate was found to be accelerated in the rabbit animal model. The study was conducted under conditions that reflected the clinical requirements—the prostheses were sutured in the end-to-side fashion and the long-term end point of prosthesis healing was assessed. The regeneration of the vessel wall in terms of endothelialization, smooth cell infiltration and the presence of collagen fibers was observed after six months in vivo. A part of the grafts failed due to the rapid degradation rate of the PLCL copolymer.
  • Item
    Generating standardized image data for testing and calibrating quantification of volumes, surfaces, lengths, and object counts in fibrous and porous materials using X-ray microtomography
    (John Wiley & Sons Inc., 2018-01-01) Bartoš Martin; Tomášek Petr; Malečková Anna; Jiřík Miroslav; Kural Tomáš; Horáková Jana; Lukáš David; Suchý Tomáš; Kochová Petra; Hubálek-Kalbáčová Marie; Králíčková Milena; Tonar Zbyněk
  • Item
    Physical Analysis of Pulse Low-Dynamic Magnetic Field Applied in Physiotherapy
    (Springer, Singapore, 2019-01-01) Richter Aleš; Bartoš Martin; Ferková Želmíra